Dongquan Chen, Ph.D., MSHI

Research Assistant Professor
Bioinformatician

Education/Training:

Norman Bethune University of Medical Sciences MD 1986 Medicine
Mount Sinai-NYU Medical Center PhD 1999 Biomedical Sciences
University of Alabama at Birmingham MS 2002 Health Informatics

Positions:

  • 1996-1998 Graduate Assistant, Cornell University Medical College, New York
  • 1999-2000 Research Scientist, Vaxin Pharmaceuticals, Inc., Birmingham, Alabama
  • 1999-2001 Research Assistant, Health Informatics Program, SHRP University of Alabama at Birmingham, Birmingham, Alabama
  • 2000 to 2003 Postdoctoral Fellow in Bioinformatics, Genetics Laboratory, NIDDK Clinical Nutrition Sciences Research Center, SHRP University of Alabama at Birmingham, Birmingham, Alabama
  • 2001 to 2003 Postdoctoral Trainee of Applied Informatics Health Informatics Program, SHRP, University of Alabama at Birmingham, Birmingham, Alabama
  • 2003 to present Bioinformatician, Biostatistics and Bioinformatics Unit /Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL
  • 2003 to present Research Assistant Professor, Medical Statistics Section, Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.

Honors:

  • National Research Services Award (NRSA) from NLM, NIH
  • CUNY Fellowship for Ph.D. program in Biomedical Sciences

Selected Publications (in chronological order):

  1. Chen DQ , Wu D-C, Wang R-Z. The Spleen PFC Changes Induced by Tritiated-Water in LACA Mice. Chinese J of Radiation Medicine and Radiological Protection, 10(1):20-22, 1990.
  2. Chen D-Q , Li X-Q, Chen L, Wang R-Z. The Biodistribution of 125-I-Labeled Anti-Ferritin (IgG) Daunomycin Immunoconjugate in Hepatoma Engrafted Nude Mice. Chinese J of Immunology, 7(5):306-308, 1991.
  3. Li X-Q, Chen D-Q, Wang R-Z. Specific Experimental Radioimmunotherapy and Chemoimmunotherapy of Hepatoma Grafts in Nude Mice. Clinical Research of the Infectious Diseases, 4(1):7-10, 1991.
  4. Chen D-Q , Chen L, Zhong WQ, Wang R-Z. The Biodistribution and (gamma-image of 131-I-Labeled Anti-Ferritin-Daunomycin Immunoconjugate in the Engrafted Nude Mice, Chinese J of Microbiology and Immunology, 13:117, 1991.
  5. Chen D-Q , Li X-Q, Chen L, Zhong WQ, Wang R-Z. Potentials for Targeting Hepatoma with Anti-Ferritin (IgG)-Daunomycin Immunoconjugate: In Vitro and In Vivo Studies, Chinese J of Cancer Research, 3:34-38, 1993.
  6. Morse L, Chen D-Q, Franklin D, Xiong Y, Chen-Kiang S. Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18-ink-4c and IL-6. Immunity. 6:47-56, 1997.

Abstracts

  1. Chen D-Q , Chen L, Wang R-Z, Li X-Q. In Vitro & In Vivo Specific Killing Effects of AHFI-Daunomycin Immunoconjugate on HCC Cells. Proceedings of The 10th Asia and Pacific Cancer Conference. Page 315. Beijing, China. International Academic Publishers. August 20-23, 1991.
  2. Altmeyer A, Chen D-Q, Morse L, Bornkamm G, Reed J, Chen-Kiang S. Activation of the CDK inhibitor p18 precedes Bcl-2 independent programmed cell death during B cell terminal differentiation. Keystone Symposia. Apoptosis and Programmed Cell Death. Page 52. Tamarron, Colorado. February 18-23, 1997.
  3. Chen D-q , Trevejo J, Sarbassov D, Almeyer A, Yu P-J, Falck-Pedersen E and Chen-Kiang S. 1999. Reversal of Epstein-Barr Virus Immortalization of Human B cells by p18 INK4C –induced proteolysis of LMP1. Keystone Symposia on Molecular and Cellular Biology. C1 “B Lymphocyte Biology and Disease”. Taos, New Mexico. February 8-14, 1999.
  4. Chen D-Q and Orthner H. Personal Agent for Easier Access of Biological Information. A Medical Informatics Odyssey: Visions of the Future and Lessons from the Past. Proceedings of Annual Symposium of American Medical Association. Washington , DC . November 3-7, 2001
  5. Sell S, Kekes-Szabo T, Tullis C, Song C, Chen, D-Q,Wang J. SNP-defined diabetes haplotype in a genetic isolate. http://www.cgr.ki.se/cgr/groups/brookes/snp2001/abstracts_posters.htm
  6. Sell S, Kekes-Szabo T, Tullis C, Song C, Chen D-Q. Wang J. SNP-defined Type 2 Diabetes-Susceptibility haplotype upstream of KRML1 locus. Diabetes. (In press)
  7. Sell S, Kekes-Szabo T, Chen D-Q, Song C-Y, Baier L, Traurig M, Hanson R, et al. UABSNP58 on Human Chromosome 20 is Associated with Insulin Resistance. (In press)

Research Support:

CA-13148 (LoBuglio) 03/01/2000 - 02/28/2005
NIH/NCI
Cancer Center Core Support Grant

This grant supports the leadership, clinical and basic science program leaders, developmental programs, and shared resources for the Comprehensive Cancer Center at the University of Alabama at Birmingham. The Biostatistics and Bioinformatics Shared Facility, directed by Dr. Seng-jaw Soong, provides comprehensive statistical and bioinformatics support for study design, data management, computer programming, and analysis for the members of the Cancer Center. Dr. Chen provides bioinformatics support.